Guatemala vs Panama Prediction – Winner Panama | World Cup Qualifiers 14 Nov 2025

Published 13/11/2025 /

Guatemala enter a high-stakes home tie with slim margins in Group A, while Panama arrive protecting a narrow points advantage in the table.
Panama are unbeaten away in the group so far and have conceded just once on the road, which suits a pragmatic approach in a tricky away venue.
The last meeting finished 1–1 in Panama City, underscoring a competitive matchup even with Panama’s broader historical edge.

Head-to-head and form

Panama have dominated the series since 2005: 11 wins for Panama, 1 for Guatemala, and 5 draws overall.
Guatemala have not beaten Panama since August 2005, highlighting the long-standing edge for Los Canaleros.
The reverse fixture in September ended 1–1, keeping both sides in contention heading into the run-in.

Key comparison

Metric	Guatemala	Panama
H2H since 2005	1 win vs Panama’s 11, 5 draws overall	11 wins vs Guatemala’s 1, 5 draws overall
Last meeting	Drew 1–1 away in Panama City on 8 Sep 2025	Drew 1–1 at home vs Guatemala on 8 Sep 2025
Group A position context	One point behind Panama entering this round per recent previews	Second in Group A with a one-point edge over Guatemala per recent previews
Upcoming fixture info	Hosts at Estadio Manuel Felipe Carrera, 14 Nov 2025, 02:00 UTC	Away at Estadio Manuel Felipe Carrera, 14 Nov 2025, 02:00 UTC

Reasons to back Panama

H2H dominance: 11 wins in 17 meetings since 2005 shows a consistent matchup edge.
Away resilience: unbeaten away in the group with only one goal conceded, fitting a results-first plan.
Guatemala’s trend: recent stage has been win-light, keeping pressure high against a disciplined opponent.

Betting tips

Main pick: Panama to win, leveraging sustained H2H superiority and better recent away profile.
Safer angle: Panama Draw No Bet, protecting against another tight draw like the 1–1 in September.
Goals lean: Under 2.5 goals, supported by the 1–1 reverse fixture and generally cagey recent head-to-heads.

Match context and stakes

Group A remains finely poised, with the final rounds set for a dramatic finish across CONCACAF qualifying.
Panama’s single-point cushion heightens the incentive to manage the game state, while Guatemala face must-not-lose pressure at home.

Possible Panama setup

Panama could stick with a pragmatic 5–4–1/3–4–2–1 shape featuring Orlando Mosquera in goal, a back line of Michael Amir Murillo, Jiovany Ramos, Fidel Escobar, Andrés Andrade, and Éric Davis, and José Fajardo leading the line.
That configuration complements their away form, compact shape, and set-piece threat while limiting transition space for the hosts.

Final verdict

Pick: Panama to win, with a cautious secondary cover on Draw No Bet given the recent 1–1 draw and away-game variance.
If goals are scarce again, a narrow 0–10–1 correct score aligns with Panama’s travel profile and the matchup’s recent rhythm.

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